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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1774 details
Primary information
Hemolytik ID1774
PMID17547385
YEAR2007
SEQUENCEGFTicGKTicGFTicGKTicKKKK
LENGTH16
NAMEPeptide-32
C-ter ModificationAmidation
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryL
Modified ResiduesTic= tetrahydroisoquinolinecarboxylic acid
FUNCTIONAntibiotic
ACTIVITY4.9% hemolysis at 25µM
RBCs SOURCEMouse
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesNA
SMILESNA
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEDe novo design of selective antibiotic peptides by incorporation of unnatural amino acids.
AUTHORSHicks RP,Bhonsle JB,Venugopal D,Koser BW
JOURNALJ Med Chem. 2007 Jun 28;50(13):3026-36. Epub 2007 Jun 5.