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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1721 details
Primary information
Hemolytik ID1721
PMID17065623
YEAR2006
SEQUENCERKKWFW
LENGTH6
NAMEPAF26
C-ter ModificationAmidation
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntifungal
ACTIVITY<0.3% hemolysis at 100µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCSCC
SMILESN[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEStudies on the mode of action of the antifungal hexapeptide PAF26.
AUTHORSMunoz A,Lopez-Garcia B, Marcos, Jose ,Marcos J
JOURNALAntimicrob Agents Chemother. 2006 Nov;50(11):3847-55.