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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1656 details
Primary information
Hemolytik ID1656
PMID16142907
YEAR2005
SEQUENCEKWKKLLKKLLaLLKKLLK
LENGTH18
NAMEKLW-K11-a
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified Residuesa=Nala (Ala-peptoid)
FUNCTIONAntimicrobial
ACTIVITY~50% hemolysis at 50µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHHHHHHHHHHHTC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLECell selectivity and mechanism of action of antimicrobial model peptides containing peptoid residues.
AUTHORSSong YM,Park Y,Lim SS,Yang ST,Woo ER,Park IS,Lee JS,Kim JI,Hahm KS,Kim Y
JOURNALBiochemistry. 2005 Sep 13;44(36):12094-106.