Primary information |
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Hemolytik ID | 1650 |
PMID | 16142907 |
YEAR | 2005 |
SEQUENCE | KWKKLLKKLaKLLKKLLK |
LENGTH | 18 |
NAME | KLW-L10-a |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | a=Nala (Ala-peptoid) |
FUNCTION | Antimicrobial |
ACTIVITY | 20% hemolysis at 100µM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CGGGTHHHHHHHHHHHTC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Cell selectivity and mechanism of action of antimicrobial model peptides containing peptoid residues. |
AUTHORS | Song YM,Park Y,Lim SS,Yang ST,Woo ER,Park IS,Lee JS,Kim JI,Hahm KS,Kim Y |
JOURNAL | Biochemistry. 2005 Sep 13;44(36):12094-106. |