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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1645 details
Primary information
Hemolytik ID1645
PMID16137634
YEAR2005
SEQUENCELLIILRRRIRKQAHAHSK
LENGTH18
NAMEpVEC(615–632)
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONCPP
ACTIVITY18.1±0.3% hemolysis at 50µM
RBCs SOURCEBovine
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTTTCGGGHHHHHHHHCC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLECell-penetrating peptides: a comparative membrane toxicity study.
AUTHORSSaar K,Lindgren M,Hansen M,Eiriksdottir E,Jiang Y,Rosenthal-Aizman K,Sassian M
JOURNALAnal Biochem. 2005 Oct 1;345(1):55-65.