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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1643 details
Primary information
Hemolytik ID1643
PMID16137634
YEAR2005
SEQUENCERQIKIWFQNRRMKWKK
LENGTH16
NAMEpAntp(43–58)
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONCPP
ACTIVITY20.0±1.8% hemolysis at 50µM
RBCs SOURCEBovine
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCCCCCCSCCCC
SMILESN[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1kz0A NA NA NA NA Q25208
from
43
TO
58
NA NA
Reference Informaiton
ARTICLECell-penetrating peptides: a comparative membrane toxicity study.
AUTHORSSaar K,Lindgren M,Hansen M,Eiriksdottir E,Jiang Y,Rosenthal-Aizman K,Sassian M
JOURNALAnal Biochem. 2005 Oct 1;345(1):55-65.