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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1608 details
Primary information
Hemolytik ID1608
PMID15298176
YEAR2004
SEQUENCEGLFGVLAKVAAHVVPAIAEHF
LENGTH21
NAMEMac
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITY100% hemolysis at 100µM
RBCs SOURCERabbit
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCTTTTTSGGGTTTGGGTCCC
SMILESNCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P82066 NA NA NA NA NA
Reference Informaiton
ARTICLEStructure-activity relationship of an antibacterial peptide, maculatin 1.1, from the skin glands of the tree frog, Litoria genimaculata.
AUTHORSNiidome T,Kobayashi K,Arakawa H,Hatakeyama T
JOURNALJ Pept Sci. 2004 Jul;10(7):414-22.