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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1589 details
Primary information
Hemolytik ID1589
PMID15127790
YEAR2004
SEQUENCEAKKVFKRLGIGAVLWVLTTG
LENGTH20
NAMEHM1
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY46% hemolysis at 100µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTTSTTTSSCSSCCCSSTTC
SMILESN[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEDesign of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12).
AUTHORSPark Y,Kim HN,Park SN,Jang SH,Choi CH,Lim HT
JOURNALBiotechnol Lett. 2004 Mar;26(6):493-8.