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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1521 details
Primary information
Hemolytik ID1521
PMID20617807
YEAR2010
SEQUENCEKWKLFKKIGAVLKVL
LENGTH15
NAMEK7 (Me3)
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYHD50 =164.0μM
RBCs SOURCESheep
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCTTHHHHHHHHTCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2jmyA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLELysine N(epsilon)-trimethylation, a tool for improving the selectivity of antimicrobial peptides.
AUTHORSFernandez-Reyes M,Diaz D,de la Torre BG,Cabrales-Rico A,Valles-Miret M,Jimenez-Barbero J,Andreu D
JOURNALJ Med Chem. 2010 Aug 12;53(15):5587-96. doi: 10.1021/jm100261r.