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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1469 details
Primary information
Hemolytik ID1469
PMID20195659
YEAR2011
SEQUENCEINWKKLLDAAKQIL
LENGTH14
NAMEPolybia N2-MP1
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITYEC50 =26μM
RBCs SOURCERabbit
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHHHHTTTC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEThe effect of acidic residues and amphipathicity on the lytic activities of mastoparan peptides studied by fluorescence and CD spectroscopy.
AUTHORSLeite NB,da Costa LC,Dos Santos Alvares D,Dos Santos Cabrera MP,de Souza BM,Palma MS
JOURNALAmino Acids. 2011 Jan;40(1):91-100. doi: 10.1007/s00726-010-0511-9. Epub 2010 Mar 1.