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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1466 details
Primary information
Hemolytik ID1466
PMID20195659
YEAR2011
SEQUENCEIDWLKLGKMVMDVL
LENGTH14
NAMEPolybia MP3
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITYEC50 =50μM
RBCs SOURCERabbit
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCTTTSSSSSSSCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P84914 NA NA NA NA NA
Reference Informaiton
ARTICLEThe effect of acidic residues and amphipathicity on the lytic activities of mastoparan peptides studied by fluorescence and CD spectroscopy.
AUTHORSLeite NB,da Costa LC,Dos Santos Alvares D,Dos Santos Cabrera MP,de Souza BM,Palma MS
JOURNALAmino Acids. 2011 Jan;40(1):91-100. doi: 10.1007/s00726-010-0511-9. Epub 2010 Mar 1.