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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1458 details
Primary information
Hemolytik ID1458
PMID19804724
YEAR2009
SEQUENCEMQFITDLIKKAVDFFKGLFGNK
LENGTH22
NAMEWarnericin RK
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY100% hemolysis at 200μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHHHHHHHTTCSSSSCC
SMILESN[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA F4ZBW5 NA NA NA
Reference Informaiton
ARTICLEDetergent-like activity and alpha-helical structure of warnericin RK, an anti-Legionella peptide.
AUTHORSVerdon J,Falge M,Maier E,Bruhn H,Steinert M,Faber C,Benz R
JOURNALBiophys J. 2009 Oct 7;97(7):1933-40. doi: 10.1016/j.bpj.2009.06.053.