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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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1378 details
Primary information
Hemolytik ID1378
PMID19544481
YEAR2009
SEQUENCELKKWLKK
LENGTH7
NAMEL2K4W4
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY4.90% hemolysis at 50μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSTTTC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA A7I3C8
from
454
TO
460		 NA H2U7E4
from
457
TO
463		 NA NA
Reference Informaiton
ARTICLEDe novo generation of antimicrobial LK peptides with a single tryptophan at the critical amphipathic interface.
AUTHORSKang SJ,Won HS,Choi WS
JOURNALJ Pept Sci. 2009 Sep;15(9):583-8. doi: 10.1002/psc.1149.