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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1367 details
Primary information
Hemolytik ID1367
PMID19524300
YEAR2009
SEQUENCERFGRFLRKIRRFRPKVTITIQ
LENGTH21
NAMEC1-21
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONImmunomodulatory and Antimicrobial
ACTIVITY40% hemolysis at 40μM
RBCs SOURCEChicken
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHHHTTSCSCCSSCCC
SMILESN[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEIdentification of chicken cathelicidin-2 core elements involved in antibacterial and immunomodulatory activities.
AUTHORSvan Dijk A,Molhoek EM,Veldhuizen EJ,Bokhoven JL,Wagendorp E,Bikker F
JOURNALMol Immunol. 2009 Aug;46(13):2465-73. doi: 10.1016/j.molimm.2009.05.019. Epub 2009 Jun 12.