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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1365 details
Primary information
Hemolytik ID1365
PMID19524300
YEAR2009
SEQUENCERFGRFLRKIRRFRPKVTITIQGSARFG
LENGTH27
NAMEC1-27
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONImmunomodulatory and Antimicrobial
ACTIVITY50% hemolysis at 40μM
RBCs SOURCEChicken
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCHHHHHHHHHHSCCCSCCCGGGGGCC
SMILESN[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA Q2IAL7
from
128
TO
154		 NA A7M6V5
from
187
TO
213		 NA NA
Reference Informaiton
ARTICLEIdentification of chicken cathelicidin-2 core elements involved in antibacterial and immunomodulatory activities.
AUTHORSvan Dijk A,Molhoek EM,Veldhuizen EJ,Bokhoven JL,Wagendorp E,Bikker F
JOURNALMol Immunol. 2009 Aug;46(13):2465-73. doi: 10.1016/j.molimm.2009.05.019. Epub 2009 Jun 12.