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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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1363 details
Primary information
Hemolytik ID1363
PMID19445503
YEAR2009
SEQUENCEWVLVLRlGY
LENGTH9
NAMEdVVRG
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY11±9% hemolysis at 15μM
RBCs SOURCESheep
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSSCCCCC
SMILESN[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEBroad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.
AUTHORSRathinakumar R, Walkenhorst, William ,Walkenhorst WF
JOURNALJ Am Chem Soc. 2009 Jun 10;131(22):7609-17. doi: 10.1021/ja8093247.