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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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1284 details
Primary information
Hemolytik ID1284
PMID19132829
YEAR2009
SEQUENCEVOL-hpa-PVOL-hpa-P
LENGTH10
NAMEGS1
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicCyclic
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesOrnithine, Hpa= homophenylalanine
FUNCTIONAntimicrobial
ACTIVITYHC50=7.0(±0.3)μM
RBCs SOURCESheep
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesNA
SMILESNA
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLETherapeutic index of gramicidin S is strongly modulated by D-phenylalanine analogues at the beta-turn.
AUTHORSSolanas C,de la Torre BG,Fernandez-Reyes M,Santiveri CM,Jimenez MA,Rivas L,Jimenez AI,Andreu D
JOURNALJ Med Chem. 2009 Feb 12;52(3):664-74. doi: 10.1021/jm800886n.