Primary information |
---|
Hemolytik ID | 1271 |
PMID | 19104020 |
YEAR | 2009 |
SEQUENCE | GIGKFIHAVKKWGKTFIGEIAKS |
LENGTH | 23 |
NAME | Ac-MK5E |
C-ter Modification | Amidation |
N-ter Modification | Acetylation |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | EC25 >400μM |
RBCs SOURCE | Human |
Secondary information |
---|
Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCTTHHHHTTGGGTCCCGGGC |
SMILES | NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C)C(=O)N[C@H](O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)O.CC(C)C.C.C.C.C.C |
External Links |
---|
PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
|
Reference Informaiton |
---|
ARTICLE | Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum. |
AUTHORS | Bagheri M,Beyermann M |
JOURNAL | Antimicrob Agents Chemother. 2009 Mar;53(3):1132-41. doi: 10.1128/AAC.01254-08. Epub 2008 Dec 22. |