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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

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1263 details
Primary information
Hemolytik ID1263
PMID18852279
YEAR2008
SEQUENCEKWKKFKKIGAVLKKL
LENGTH15
NAMEK414
C-ter ModificationAmidation
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY3% hemolysis at 64μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCTTTHHHHHHHTTC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLELysine-enriched cecropin-mellitin antimicrobial peptides with enhanced selectivity.
AUTHORSSato H
JOURNALAntimicrob Agents Chemother. 2008 Dec;52(12):4463-5. doi: 10.1128/AAC.00810-08. Epub 2008 Oct 13.