Primary information |
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Hemolytik ID | 1211 |
PMID | 18455267 |
YEAR | 2008 |
SEQUENCE | RLCYTRGRFTVCV |
LENGTH | 13 |
NAME | PC109 |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 12-25% hemolysis at 80μg/ml |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CEEEETTEEEECC |
SMILES | N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Correlation between simulated physicochemical properties and hemolycity of protegrin-like antimicrobial peptides: predicting experimental toxicity. |
AUTHORS | Langham AA,Khandelia H,Schuster B,Waring AJ,Lehrer RI |
JOURNAL | Peptides. 2008 Jul;29(7):1085-93. doi: 10.1016/j.peptides.2008.03.018. Epub 2008 Mar 28. |