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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1165 details
Primary information
Hemolytik ID1165
PMID18455267
YEAR2008
SEQUENCERGGRLCYCRGWICFCVGR
LENGTH18
NAMEPC4
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY>50% hemolysis at 80μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSCCCCCTTCCCCCCCC
SMILESN[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLECorrelation between simulated physicochemical properties and hemolycity of protegrin-like antimicrobial peptides: predicting experimental toxicity.
AUTHORSLangham AA,Khandelia H,Schuster B,Waring AJ,Lehrer RI
JOURNALPeptides. 2008 Jul;29(7):1085-93. doi: 10.1016/j.peptides.2008.03.018. Epub 2008 Mar 28.