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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1089 details
Primary information
Hemolytik ID1089
PMID17158938
YEAR2007
SEQUENCEKWKSFLKTFKSLKKTVLHTLLKAISS
LENGTH26
NAMEA12L/A20L
C-ter ModificationAmidation
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYMHC =8μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCGGGHHHHHHHTTSHHHHHHHHHCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLERole of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.
AUTHORSChen Y,Guarnieri MT,Vasil AI,Vasil ML,Mant CT
JOURNALAntimicrob Agents Chemother. 2007 Apr;51(4):1398-406. Epub 2006 Dec 11.