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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1073 details
Primary information
Hemolytik ID1073
PMID20153801
YEAR2010
SEQUENCEFVLPLVMCKILRKC
LENGTH14
NAMEJaponicin-1Npb
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY3.40% hemolysis at 80μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCHHHHHHHGGGC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA D0ES74
from
58
TO
71
NA NA
Reference Informaiton
ARTICLENovel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri.
AUTHORSLu Z,Zhai L,Wang H,Che Q,Wang D,Feng F,Zhao Z
JOURNALBiochimie. 2010 May;92(5):475-81. doi: 10.1016/j.biochi.2010.01.025. Epub 2010 Feb 12.