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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1042 details
Primary information
Hemolytik ID1042
PMID11087404
YEAR2000
SEQUENCERRWCFRVCYRGFCYRKCR
LENGTH18
NAMEPM1
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY100% hemolysis at 21.3μg/ml
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCCCCSSSCCCCCC
SMILESN[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1rkkA NA P14215 NA NA NA NA NA
Reference Informaiton
ARTICLEInteraction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers.
AUTHORSZhang L,Scott MG,Yan H,Mayer LD
JOURNALBiochemistry. 2000 Nov 28;39(47):14504-14.