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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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1025 details
Primary information
Hemolytik ID1025
PMID18081258
YEAR2008
SEQUENCEGLPVCGETCVGGTCNTPGCTCSWPVCTRN
LENGTH29
NAMEKatala B1
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicCyclic
StereochemistryL
Modified ResiduesNone
FUNCTIONAnti-HIV
ACTIVITYHD50 =11.7μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCSSHHHHCCCCCSSCCCCSSCCSCC
SMILESNCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2khbA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEAnti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis.
AUTHORSWang CK,Colgrave ML,Gustafson KR,Ireland DC,Goransson U
JOURNALJ Nat Prod. 2008 Jan;71(1):47-52. Epub 2007 Dec 15.