Primary information |
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Hemolytik ID | 1024 |
PMID | 15149180 |
YEAR | 2004 |
SEQUENCE | KLFKRHLKWKII |
LENGTH | 12 |
NAME | SC4 |
C-ter Modification | Amidation |
N-ter Modification | Conjugated with lauric acid |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | <15% hemolysis at 3μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCTTTSCCCCCC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Promotion of peptide antimicrobial activity by fatty acid conjugation. |
AUTHORS | Chu-Kung, Alexander ,Chu-Kung AF,Bozzelli KN,Lockwood NA,Haseman JR,Mayo KH |
JOURNAL | Bioconjug Chem. 2004 May-Jun;15(3):530-5. |