Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0004931
Inhibitor ClassQuinazoline
Molecule Name in Refrence Article11b
IUPAC NameN-(3-chlorophenyl)-6,7,8-trimethoxyquinazolin-4-amine
FormulaC17H16ClN3O3
Mass345.78
Exact Mass345.0880191
Composition C (59.05%), H (4.66%), Cl (10.25%), N (12.15%), O (13.88%)
Atom Count40
PI9.8
Smilesc12cc(c(c(c1ncnc2Nc1cc(ccc1)Cl)OC)OC)OC
InChI1S/C17H16ClN3O3/c1-22-13-8-12-14(16(24-3)15(13)23-2)19-9-20-17(12)21-11-6-4-5-10(18)7-11/h4-9H,1-3H3
,(H,19,20,21)
InChIKeyKXYHTLLUNBBBQS-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference8879541
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link 5328818
Drug Bank Link -
ChemSpider Link 4485980
ChEMBL Link CHEMBL228506
 
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