Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0004494
Inhibitor ClassPyrido-pyrimidine
Molecule Name in Refrence Article4a
IUPAC Name4-amino-7-[(2-hydroxyethyl)amino]pyrido[2,3-d]pyrimidine-6-carbonitrile
FormulaC10H10N6O
Mass230.226
Exact Mass230.091609
Composition C (52.17%), H (4.38%), N (36.5%), O (6.95%)
Atom Count27
PI9.92
Smilesc1(ncnc2c1cc(c(n2)NCCO)C#N)N
InChI1S/C10H10N6O/c11-4-6-3-7-8(12)14-5-15-10(7)16-9(6)13-1-2-17/h3,5,17H,1-2H2,(H3,12,13,14,15,16)
InChIKeyWSKJBEAUZWPRKV-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference22000924
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesCDK4/D | CDK2/A | ALL
Pub Chem Link 56935337
Drug Bank Link -
ChemSpider Link 28484576
ChEMBL Link CHEMBL1910268
 
TOP