Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0004436
Inhibitor ClassAnilino-quinazoline
Molecule Name in Refrence Article6g
IUPAC Name8-[(1H-indazol-5-yl)amino]-1-[3-(morpholin-4-yl)propyl]-1H,2H-[1,3]oxazolo[4,5-g]quinazolin-2-one
FormulaC23H23N7O3
Mass445.4738
Exact Mass445.1862376
Composition C (62.01%), H (5.2%), N (22.01%), O (10.77%)
Atom Count56
PI10.34
SmilesC1OCCN(C1)CCCn1c(=O)oc2c1cc1c(c2)ncnc1Nc1ccc2[nH]ncc2c1
InChI1S/C23H23N7O3/c31-23-30(5-1-4-29-6-8-32-9-7-29)20-11-17-19(12-21(20)33-23)24-14-25-22(17)27-16-2-3-1
8-15(10-16)13-26-28-18/h2-3,10-14H,1,4-9H2,(H,26,28)(H,24,25,27)
InChIKeyVOAPURHNWAYKRM-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference22818848
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 28509263
ChEMBL Link -
 
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