Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0004044
Inhibitor ClassAnilino-quinoline
Molecule Name in Refrence Article17c compound
IUPAC Name4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-methoxy-8-[2-(morpholin-4-yl)ethoxy]benzo[g]quinoline-3-carbonitrile
FormulaC28H26Cl2N4O4
Mass553.436
Exact Mass552.1331108
Composition C (60.77%), H (4.74%), Cl (12.81%), N (10.12%), O (11.56%)
Atom Count64
PI10.93
Smilesc1(c2c(ncc1C#N)cc1c(c2)cc(c(c1)OCCN1CCOCC1)OC)Nc1cc(c(cc1Cl)Cl)OC
InChI1S/C28H26Cl2N4O4/c1-35-25-14-24(21(29)13-22(25)30)33-28-19(15-31)16-32-23-10-18-12-27(26(36-2)11-17(
18)9-20(23)28)38-8-5-34-3-6-37-7-4-34/h9-14,16H,3-8H2,1-2H3,(H,32,33)
InChIKeyUNZHPVUBBKLAJR-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference16161995
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesAKT | cdk4 | MK2 | Src | ALL
Pub Chem Link 5330437
Drug Bank Link -
ChemSpider Link 4487588
ChEMBL Link CHEMBL195029
 
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