Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003931
Inhibitor ClassQuinazoline
Molecule Name in Refrence Article4 compound
IUPAC NameN-[(1R)-1-phenylethyl]-3H-pyrimido[5,4-b]indol-4-amine
FormulaC18H16N4
Mass288.3464
Exact Mass288.1374965
Composition C (74.98%), H (5.59%), N (19.43%)
Atom Count38
PI5.68
Smilesc12nc3c(c1nc[nH]c2N[C@@H](c1ccccc1)C)cccc3
InChI1S/C18H16N4/c1-12(13-7-3-2-4-8-13)21-18-17-16(19-11-20-18)14-9-5-6-10-15(14)22-17/h2-12,21H,1H3,(H,1
9,20)/t12-/m1/s1
InChIKeyALVAPOXOHZKAAJ-GFCCVEGCSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference11520212
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 23189140
ChEMBL Link CHEMBL102651
 
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