Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003888
Inhibitor ClassIndolinone
Molecule Name in Refrence Article4f compound
IUPAC Name(3Z)-6-phenyl-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one
FormulaC23H20N2O
Mass340.4177
Exact Mass340.1575633
Composition C (81.15%), H (5.92%), N (8.23%), O (4.7%)
Atom Count46
PI4.55
SmilesC1(=C/c2[nH]c3c(c2)CCCC3)/C(=O)Nc2c1ccc(c2)c1ccccc1
InChI1S/C23H20N2O/c26-23-20(14-18-12-17-8-4-5-9-21(17)24-18)19-11-10-16(13-22(19)25-23)15-6-2-1-3-7-15/h1
-3,6-7,10-14,24H,4-5,8-9H2,(H,25,26)/b20-14-
InChIKeyBCEALSZPAPLOJG-ZHZULCJRSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference10893303
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesFGFR1 | p60c-Src | VEGFR2 | PDGFR beta | ALL
Pub Chem Link 5329159
Drug Bank Link -
ChemSpider Link 4486321
ChEMBL Link CHEMBL313746
 
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