Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003885
Inhibitor ClassIndolinone
Molecule Name in Refrence Article4c compound
IUPAC Name(3Z)-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-2,3-dihydro-1H-indole-5-sulfonamide
FormulaC17H17N3O3S
Mass343.4
Exact Mass343.0990621
Composition C (59.46%), H (4.99%), N (12.24%), O (13.98%), S (9.34%)
Atom Count41
PI3.95
SmilesS(=O)(=O)(c1cc2/C(=C/c3[nH]c4c(c3)CCCC4)/C(=O)Nc2cc1)N
InChI1S/C17H17N3O3S/c18-24(22,23)12-5-6-16-13(9-12)14(17(21)20-16)8-11-7-10-3-1-2-4-15(10)19-11/h5-9,19H,
1-4H2,(H,20,21)(H2,18,22,23)/b14-8-
InChIKeyFHSRUXRMSRJDQV-ZSOIEALJSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference10893303
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesPDGFR beta | FGFR1 | VEGFR2 | p60c-Src | ALL
Pub Chem Link 5329156
Drug Bank Link DB08039
ChemSpider Link 4486318
ChEMBL Link CHEMBL88483
 
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