Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003752
Inhibitor ClassPyrido-pyrimidine
Molecule Name in Refrence Article26 compound
IUPAC Name6-(2,6-dichlorophenyl)-2-[(2-hydroxyethyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
FormulaC16H14Cl2N4O2
Mass365.214
Exact Mass364.0493811
Composition C (52.62%), H (3.86%), Cl (19.41%), N (15.34%), O (8.76%)
Atom Count38
PI8.63
Smilesn1(c2nc(ncc2cc(c1=O)c1c(Cl)cccc1Cl)NCCO)C
InChI1S/C16H14Cl2N4O2/c1-22-14-9(8-20-16(21-14)19-5-6-23)7-10(15(22)24)13-11(17)3-2-4-12(13)18/h2-4,7-8,2
3H,5-6H2,1H3,(H,19,20,21)
InChIKeyGOWKLVGETIDUTE-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9703473
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesFGFr | c-Src | PDGFr | ALL
Pub Chem Link 5327873
Drug Bank Link -
ChemSpider Link 4485043
ChEMBL Link CHEMBL111618
 
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