Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003749
Inhibitor ClassPyrido-pyrimidine
Molecule Name in Refrence Article23 compound
IUPAC Name6-(2,6-dichlorophenyl)-8-methyl-2-[(propan-2-yl)amino]-7H,8H-pyrido[2,3-d]pyrimidin-7-one
FormulaC17H16Cl2N4O
Mass363.241
Exact Mass362.0701166
Composition C (56.21%), H (4.44%), Cl (19.52%), N (15.42%), O (4.4%)
Atom Count40
PI9.03
Smilesn1(c2nc(ncc2cc(c1=O)c1c(Cl)cccc1Cl)NC(C)C)C
InChI1S/C17H16Cl2N4O/c1-9(2)21-17-20-8-10-7-11(16(24)23(3)15(10)22-17)14-12(18)5-4-6-13(14)19/h4-9H,1-3H3
,(H,20,21,22)
InChIKeyGWRZAKQWUQRPDF-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9703473
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesc-Src | PDGFr | FGFr | ALL
Pub Chem Link 5327870
Drug Bank Link -
ChemSpider Link 4485040
ChEMBL Link CHEMBL109759
 
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