Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003748
Inhibitor ClassPyrido-pyrimidine
Molecule Name in Refrence Article22 compound
IUPAC Name6-(2,6-dichlorophenyl)-2-(ethylamino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
FormulaC16H14Cl2N4O
Mass349.215
Exact Mass348.0544665
Composition C (55.03%), H (4.04%), Cl (20.3%), N (16.04%), O (4.58%)
Atom Count37
PI9.31
Smilesn1(c2nc(ncc2cc(c1=O)c1c(Cl)cccc1Cl)NCC)C
InChI1S/C16H14Cl2N4O/c1-3-19-16-20-8-9-7-10(15(23)22(2)14(9)21-16)13-11(17)5-4-6-12(13)18/h4-8H,3H2,1-2H3
,(H,19,20,21)
InChIKeyFNBJMQJWFBTPGJ-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9703473
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesPDGFr | c-Src | FGFr | ALL
Pub Chem Link 5327869
Drug Bank Link -
ChemSpider Link 4485039
ChEMBL Link CHEMBL109296
 
TOP