Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003722
Inhibitor ClassIndolinone
Molecule Name in Refrence Article40 compound
IUPAC Name(3Z)-6-fluoro-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one
FormulaC13H9FN2O
Mass228.2218
Exact Mass228.0698911
Composition C (68.42%), H (3.97%), F (8.32%), N (12.27%), O (7.01%)
Atom Count26
PI4.43
SmilesC1(=C/c2[nH]ccc2)/C(=O)Nc2c1ccc(c2)F
InChI1S/C13H9FN2O/c14-8-3-4-10-11(7-9-2-1-5-15-9)13(17)16-12(10)6-8/h1-7,15H,(H,16,17)/b11-7-
InChIKeyJFVLMRYDPQMRFA-XFFZJAGNSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9651163
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesFLK-1 | IGF1R | PDGFR | ALL
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 8903368
ChEMBL Link CHEMBL87208
 
TOP