Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003703
Inhibitor ClassIndolinone
Molecule Name in Refrence Article21 compound
IUPAC Name(3Z)-5-chloro-3-{[4-(morpholin-4-yl)phenyl]methylidene}-2,3-dihydro-1H-indol-2-one
FormulaC19H17ClN2O2
Mass340.803
Exact Mass340.0978555
Composition C (66.96%), H (5.03%), Cl (10.4%), N (8.22%), O (9.39%)
Atom Count41
PI6.16
SmilesC1(=C/c2ccc(N3CCOCC3)cc2)/C(=O)Nc2c1cc(cc2)Cl
InChI1S/C19H17ClN2O2/c20-14-3-6-18-16(12-14)17(19(23)21-18)11-13-1-4-15(5-2-13)22-7-9-24-10-8-22/h1-6,11-
12H,7-10H2,(H,21,23)/b17-11-
InChIKeyDVKIICSQTRTPIE-BOPFTXTBSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9651163
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesIGF1R | PDGFR | FLK-1 | ALL
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 1789608
ChEMBL Link CHEMBL421548
 
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