Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003701
Inhibitor ClassIndolinone
Molecule Name in Refrence Article19 compound
IUPAC Name(3Z)-3-{[4-(morpholin-4-yl)phenyl]methylidene}-2,3-dihydro-1H-indol-2-one
FormulaC19H18N2O2
Mass306.3584
Exact Mass306.1368278
Composition C (74.49%), H (5.92%), N (9.14%), O (10.44%)
Atom Count41
PI6.17
SmilesC1(=C/c2ccc(N3CCOCC3)cc2)/C(=O)Nc2c1cccc2
InChI1S/C19H18N2O2/c22-19-17(16-3-1-2-4-18(16)20-19)13-14-5-7-15(8-6-14)21-9-11-23-12-10-21/h1-8,13H,9-12
H2,(H,20,22)/b17-13-
InChIKeyFWFISWZSIAJQSO-LGMDPLHJSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9651163
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesIGF1R | FLK-1 | PDGFR | ALL
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 1777330
ChEMBL Link CHEMBL86480
 
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