Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003692
Inhibitor ClassIndolinone
Molecule Name in Refrence Article1 compound
IUPAC Name(3Z)-3-{[4-(dimethylamino)phenyl]methylidene}-2,3-dihydro-1H-indol-2-one
FormulaC17H16N2O
Mass264.3217
Exact Mass264.1262631
Composition C (77.25%), H (6.1%), N (10.6%), O (6.05%)
Atom Count36
PI7.97
SmilesN1C(=O)/C(=Cc2ccc(cc2)N(C)C)/c2ccccc12
InChI1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h3-11H,1-2H3,(H,18,20)/b15
-11-
InChIKeyUAKWLVYMKBWHMX-PTNGSMBKSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9651163
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesIGF1R | PDGFR | FLK-1 | ALL
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 4510144
ChEMBL Link CHEMBL328710
 
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