Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0002270
Inhibitor ClassBenzylidene
Molecule Name in Refrence Article5 compound
IUPAC Name(5E)-5-[(3-hydroxyphenyl)methylidene]-1-(2-phenylethyl)imidazolidine-2,4-dione; dichlorane
FormulaC18H16Cl2N2O3
Mass379.237
Exact Mass378.0537978
Composition C (57.01%), H (4.25%), Cl (18.7%), N (7.39%), O (12.66%)
Atom Count41
PINo isoelectric point.
SmilesC1(=Cc2cccc(c2)O)/N(C(=O)NC1=O)CCc1ccccc1.ClCl
InChI1S/C18H16N2O3.Cl2/c21-15-8-4-7-14(11-15)12-16-17(22)19-18(23)20(16)10-9-13-5-2-1-3-6-13;1-2/h1-8,11-
12,21H,9-10H2,(H,19,22,23);/b16-12+;
InChIKeyHUMUASZSGIVPQF-CLNHMMGSSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference19268405
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 22933
ChEMBL Link -
 
TOP