Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0002031
Inhibitor ClassAnilino-quinazoline
Molecule Name in Refrence Article7i compound
IUPAC Name3-butyl-N-(4-methoxyphenyl)-2-(propan-2-yl)-3H-imidazo[4,5-g]quinazolin-8-amine
FormulaC23H27N5O
Mass389.4934
Exact Mass389.2215605
Composition C (70.92%), H (6.99%), N (17.98%), O (4.11%)
Atom Count56
PI10.99
Smilesc1(nc2cc3c(Nc4ccc(cc4)OC)ncnc3cc2n1CCCC)C(C)C
InChI1S/C23H27N5O/c1-5-6-11-28-21-13-19-18(12-20(21)27-23(28)15(2)3)22(25-14-24-19)26-16-7-9-17(29-4)10-8
-16/h7-10,12-15H,5-6,11H2,1-4H3,(H,24,25,26)
InChIKeySXOSLSSSXFMOGT-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference18313807
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link 15984355
Drug Bank Link -
ChemSpider Link 13115725
ChEMBL Link CHEMBL515600
 
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