Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0001571
Inhibitor ClassQuinazoline
Molecule Name in Refrence Article44 compound
IUPAC Namebenzyl 4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carboxylate
FormulaC22H24N4O4
Mass408.4504
Exact Mass408.1797553
Composition C (64.69%), H (5.92%), N (13.72%), O (15.67%)
Atom Count54
PINo isoelectric point.
Smilesc12c(cc(c(c1)OC)OC)ncnc2N1CCN(CC1)C(=O)OCc1ccccc1
InChI1S/C22H24N4O4/c1-28-19-12-17-18(13-20(19)29-2)23-15-24-21(17)25-8-10-26(11-9-25)22(27)30-14-16-6-4-3
-5-7-16/h3-7,12-13,15H,8-11,14H2,1-2H3
InChIKeyGMKGTICWDBTEPZ-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference18702009
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesNo activity data against other kinases present in database
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