Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0000886
Inhibitor ClassAnilino-quinoline
Molecule Name in Refrence Article56 compound
IUPAC Name4-[(3-bromophenyl)amino]-6,7-bis(methoxymethoxy)quinoline-3-carbonitrile
FormulaC20H18BrN3O4
Mass444.279
Exact Mass443.0480687
Composition C (54.07%), H (4.08%), Br (17.99%), N (9.46%), O (14.4%)
Atom Count46
PI10.65
Smilesc12c(cc(c(c1)OCOC)OCOC)ncc(c2Nc1cccc(c1)Br)C#N
InChI1S/C20H18BrN3O4/c1-25-11-27-18-7-16-17(8-19(18)28-12-26-2)23-10-13(9-22)20(16)24-15-5-3-4-14(21)6-15
/h3-8,10H,11-12H2,1-2H3,(H,23,24)
InChIKeyTUZMSVARIRHFNQ-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference10966743
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link 5328881
Drug Bank Link -
ChemSpider Link 4486043
ChEMBL Link CHEMBL111222
 
TOP