Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0000577
Inhibitor ClassAnilino-quinoline
Molecule Name in Refrence Article6a compound
IUPAC Name4-[(6-ethoxy-2-methylquinolin-4-yl)amino]-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide
FormulaC22H22N4O4S
Mass438.499
Exact Mass438.1361759
Composition C (60.26%), H (5.06%), N (12.78%), O (14.59%), S (7.31%)
Atom Count53
PI7.06
Smilesc12c(ccc(c1)OCC)nc(cc2Nc1ccc(cc1)S(=O)(=O)Nc1noc(c1)C)C
InChI1S/C22H22N4O4S/c1-4-29-17-7-10-20-19(13-17)21(11-14(2)23-20)24-16-5-8-18(9-6-16)31(27,28)26-22-12-15
(3)30-25-22/h5-13H,4H2,1-3H3,(H,23,24)(H,25,26)
InChIKeyDALCZTSFQFYNNV-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference18678492
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 24709317
ChEMBL Link CHEMBL497323
 
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