Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0000649
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1AKT1->50000 nM-------
2CaMKII->50000 nM-------
3Cdk2/cyclin E->50000 nM-------
4c-KIT-38000 nM-------
5Emt->50000 nM-------
6FGFR1->50000 nM-------
7GSK-3 beta->50000 nM-------
8IGF1R->50000 nM-------
9IKK->10000 nM-------
10Lck-4000 nM-------
11MAPKAP K2->50000 nM-------
12MEK-2500 nM-------
13Met->40000 nM-------
14P38 alphp->50000 nM-------
15PKA->50000 nM-------
16PKC alpha->50000 nM-------
17PKC delta->50000 nM-------
18PKC epsilon->50000 nM-------
19PKC theta->50000 nM-------
20Syk->50000 nM-------
21VEGFR2-8800 nM-------