| ID |
PMID |
Sequence |
Chirality |
Peptide name |
Origin |
Family |
Nature |
Sub-cellular localization |
N terminal modification |
C terminal modification |
Uptake efficiency |
Uptake mechanism |
Cancer cell lines |
Patent number |
|
| 1011 | 11087855 | rkkrrqrrr | D | D-Tat (49-57) | HIV-1 | Protein derived | Cationic | Probably cytoplasm and nucleus, nucleolus | Labelled with fluorescein with aminohexanoic space | Free | High (greater than Tat (49-57)) | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1013 | 11087855 | rrrqrrkkr | D | D-Tat (57-49) | HIV-1 | Protein derived | Cationic | Probably cytoplasm and nucleus, nucleolus | Labelled with fluorescein with aminohexanoic space | Free | High (greater than Tat (49-57)) | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1039 | 11087855 | rrrrr | D | D-R5 | Positively charged sequence | Synthetic | Cationic | Probably cytoplasm and nucleus | Labelled with fluorescein with aminohexanoic space | Free | Low (relative to Tat (49-57)) | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1040 | 11087855 | rrrrrr | D | D-R6 | Positively charged sequence | Synthetic | Cationic | Probably cytoplasm and nucleus | Labelled with fluorescein with aminohexanoic space | Free | High (comparable to Tat (49-57) and higher than R6 | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1041 | 11087855 | rrrrrrr | D | D-R7 | Positively charged sequence | Synthetic | Cationic | Probably cytoplasm and nucleus | Labelled with fluorescein with aminohexanoic space | Free | High (relative to both Tat (49-57) and R7) | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1042 | 11087855 | rrrrrrrr | D | D-R8 | Positively charged sequence | Synthetic | Cationic | Probably cytoplasm and nucleus | Labelled with fluorescein with aminohexanoic space | Free | High (relative to both Tat (49-57) and R7) | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1043 | 11087855 | rrrrrrrrr | D | D-R9 | Positively charged sequence | Synthetic | Cationic | Probably cytoplasm and nucleus | Labelled with fluorescein with aminohexanoic space | Free | High (relative to both Tat (49-57) and R7) | Probably non-endocytic pathway | Jurkat | US 6593292 |
|
| 1088 | 10998065 | klalklalkalkaalkla | D | D form of KLA | Designed Model peptide | Synthetic | Amphipathic | Cytoplasm and nucleus | Labelled with fluorescein | Amidation | Unknown | Non-endocytic pathway | Aortic endothelial cells | Unknown |
|
| 1092 | 8663410 | rqikiwfqnrrmkwkk | D | D form of pAntpHD (43-58) | Antennapedia homeodomain of drosophila | Protein derived | Amphipathic | Cytoplasm and nucleus | Biotinylation | Amidation | Similar to (pAntp) (43-58) | Non-receptor mdiated endocytic pathway | Cortical striatal cells | Unknown |
|
| 1153 | 21319732 | MDCRWRWKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (48% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1154 | 21319732 | DCRWRWKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (43% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1155 | 21319732 | DCRWRWKCXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (23%of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1156 | 21319732 | CRWRWKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (50% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1157 | 21319732 | CRWRWKCXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (33% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1158 | 21319732 | RWRWKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (30% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1159 | 21319732 | MDCRWRWKXXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (31% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1160 | 21319732 | DCRWRWKXXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (22% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1161 | 21319732 | CRWRWKXXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (34% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1162 | 21319732 | RWRWKXXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (10% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1172 | 21319732 | crwrwkcckk | D | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (52% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1174 | 21319732 | kcckwrwrck | D | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (36% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1183 | 21319732 | KMDXRWRWKCCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (48% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1184 | 21319732 | KMDXRWRWKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (18% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1185 | 21319732 | KMDXRWRWKXXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (4% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1186 | 21319732 | KMDXRWRWKCXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (70% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1187 | 21319732 | MDCRWRWKCXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Medium (38% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1197 | 21319732 | KMDXRPRPKCCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (6% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1198 | 21319732 | KMDXRPRPKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (5% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1199 | 21319732 | KMDXRPRPKCXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (6% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1200 | 21319732 | KMDCRPRPKXCKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (7% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1201 | 21319732 | KMDCRPRPKCXKK | Mod | Crot (27-39) derevative | Retal snake venom (Crotamine) | Protein derived | Cystein rich | Probably Cytosol | Labelled with K-FITC or k-FITC at N-terminus | Free | Low (9% of CyLoP1) | Probably Receptor mediated endocytic process | NIH-3T3 | US20110027300 |
|
| 1203 | 21319732 | rkkrrqrrr | D | Tat (49-57) | HIV-1 | Protein derived | Cationic | Vesicles | Labelled with K-FITC or k-FITC at N-terminus | Free | Lower than CyLoP1 | Probably endocytic process | NIH-3T3 | Unknown |
|
| 1204 | 21319732 | rrrqrrkkr | D | Tat (57-49) | HIV-1 | Protein derived | Cationic | Vesicles | Labelled with K-FITC or k-FITC at N-terminus | Free | Lower than CyLoP1 | Probably endocytic process | NIH-3T3 | Unknown |
|
| 1205 | 21319732 | rrrrrrrr | D | R8 | Positively charged sequence | Synthetic | Cationic | Vesicles | Labelled with K-FITC or k-FITC at N-terminus | Free | Lower than CyLoP1 | Probably endocytic process | NIH-3T3 | Unknown |
|
| 1236 | 21359136 | vptlk | D | Bip20 | Bax-binding domain of human Ku70 | Protein derived (Cell penetrating pentapeptides) | Unknown | Unknown | Labelled with fluorescein | Free | Unknown | Mechanisms other than endocytic and pinocytic process (Non-endocytic pathway) | DAMI cells | Unknown |
|
| 1316 | 16808894 | lliilrrrirkqahahsk | D | D form of pVEC | Murine vascular endothelial-cadherin protein | Protein derived | Probably Amphipathic | Prabably cytoplasm and nucleus | Labelled with fluorescein | Amidation | Comparable to pVEC | Probably receptor independent endocytic pathway | Human bowes melanoma cells | Unknown |
|
| 1341 | 15209161 | rsrgrlrrgairlqrg | D | Erns12 | Classical Swine Fever Virus Erns | Protein derived | Cationic | Unknown | Biotinylation | Amidation | Unknown | Unknown | EBTr cells | Unknown |
|
| 1426 | 12032302 | akvkdepqrrsarlsakpappkpepkpkkapakk | D | D form of F3 | HMGN2 Protein | Protein derived | Unknown | Cytoplasm | Labelled with fluorescein with an amino-hexanoic a | Free | Lower than L form of f3 | Energy dependent pathway | MDA-MB-435 | Unknown |
|
| 1429 | 17635150 | vrlpppvrlpppvrlppp | D | D form of Sweat Arrow Protein (SAP) | Maize gamma-Zein | Protein derived | Amphipathic | Unknown | Labelled with fluoresceine | Free | Comparable to L-SAP | Unknown | HeLa | Unknown |
|
| 1481 | 12783857 | rggrlsysrrrfststgr | D | D-SynB1 | protegrin | Protein derived | Antimicrobial | Uknown | Labelled with NBD | Free | Lower than pAntp-(43–58) and SynB5 | Unknown | K562 cells | Unknown |
|
| 1483 | 12783857 | rrlsysrrrf | D | D-SynB3 | protegrin | Protein derived | Antimicrobial | Unknown | Labelled with NBD | Free | Lower than pAntp-(43–58) and SynB5 | Unknown | K562 cells | Unknown |
|
| 1524 | 16272160 | csippevkfnpfvyli | D | D form of C105Y | Alpha1-antitrypsin (359–374) | Protein derived | Unknown | Cytoplasm | Labelled with fluoresceine/FITC | Amidation | Unknown | Unknown | HuH7, 3T3, and primary HTE cells | Unknown |
|
| 1814 | 21867915 | rrrrrrrrr | D | r9 | Positively charged sequence | Synthetic | Cationic | Plasma membrane bound | Fluorescein labelled | Amidation | 53% that of R9 | Unknown | HeLa | Unknown |
|
| 1815 | 21867915 | rrrrrrrrr | D | r9 | Positively charged sequence | Synthetic | Cationic | Plasma membrane bound | Fluorescein labelled | Amidation | 46% that of R9 | Unknown | MC57 | Unknown |
|
| 1816 | 21867915 | rrrrrrrrr | D | r9 | Positively charged sequence | Synthetic | Cationic | Cytoplasm and nucleoli | Fluorescein labelled | Amidation | Comparable to R9 | Unknown | Jurkat | Unknown |
|
| 1817 | 21867915 | rrrrrrrrrk | D | r9k | Positively charged sequence | Synthetic | Cationic | Membrane bound | Acetylation | Fluorescein labelled | Unknown | Unknown | MC57 | Unknown |
|
| 1822 | 21867915 | rqikiwfqnrrmkwkk | D | Penetratin {pAntp-(43–58)} | Antennapedia homeodomain of drosophila | Protein derived | Amphipathic | Vesicles and membrane bound | Fluorescein labelled | Amidation | Unknown | Unknown | HeLa | Unknown |
|
| 1823 | 21867915 | rqikiwfqnrrmkwkk | D | Penetratin {pAntp-(43–58)} | Antennapedia homeodomain of drosophila | Protein derived | Amphipathic | Membrane bound | Fluorescein labelled | Amidation | Unknown | Unknown | MC57 | Unknown |
|
| 1826 | 21867915 | kcfqwqrnmrkvrgppvscikr | D | hLF(38–59) peptide | Human lactoferine | Protein derived | Unknown | Membrane bound | Fluorescein labelled | Amidation | Unknown | Unknown | HeLa | Unknown |
|
| 1827 | 21867915 | kcfqwqrnmrkvrgppvscikr | D | hLF(38–59) peptide | Human lactoferine | Protein derived | Unknown | Membrane bound | Fluorescein labelled | Amidation | Unknown | Unknown | MC57 | Unknown |
|
| 1829 | 21875799 | KLULKLULKULKAULKLUGC | Mod | MAP (Aib) | Designed | Synthetic | Amphipathic | Cytoplasm and nucleus | Acetylated | Fluorescein-labeled | Higher than MAP | Unknown | A549 | Unknown |
|
| 1839 | 19228019 | crkkrrqrrr | D | cTat | HIV-1 | Protein derived | Cationic | Unknown | Conjucated to Insulin | Free | Higher than ck9 | Unknown | Rat alveolar epithelial cell monolayers (RAECM) and HepG2 | Unknown |
|
| 1840 | 19228019 | crrrrrrrrr | D | cr9 | Positively charged sequence | Synthetic | Cationic | Unknown | Conjucated to Insulin | Free | Higher than cTat and ck9 | Adsorptive transcytosis pathways | Rat alveolar epithelial cell monolayers (RAECM) and HepG3 | Unknown |
|
| 1841 | 19228019 | ckkkkkkkkk | D | ck9 | Positively charged sequence | Synthetic | Cationic | Unknown | Conjucated to Insulin | Free | lower than cTat and cr9 | Unknown | Rat alveolar epithelial cell monolayers (RAECM) and HepG4 | Unknown |
|
| 1845 | 17217340 | rrrrrrrr | D | r8 | Positively charged sequence | Synthetic | Cationic | Cytoplasm and nucleus and nucleolus at 4 degrre, while in vesicle at 37 de | Free | Labelled at the C-terminal cysteine using Alexa Fl | Unknown | Unknown | KG1a cells | Unknown |