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Details of CPPsite entry with Sequence ACRRSRRGCGRRSRRCG
Primary information
PEPTIDE SEQUENCEACRRSRRGCGRRSRRCG
CPPsite ID 2358, 2379,
PEPTIDE NAMEIA8b, IA8b L (Linear variants)
CHIRALITYL, L
LINEAR/CYCLICCyclic, Cyclic
SOURCESynthetic, Synthetic
CATEGORYArginine rich, Arginine rich
SUB CELLULAR LOCALIZATIONVesicles, Vesicles
N-TERMINAL MODIFICATIONExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer, Extended with Alanine and an 6-aminohexanoic acid (Ahx) spacer
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, All cysteines were capped with iodoacetamide
UPTAKE EFFICIENCYHigh uptake efficiency, NA
PROPOSED UPTAKE MECHANISMEndocytic pathway, Endocytic pathway
INVITRO/INVIVOIn vitro, In vitro
CELL LINEHeLa, HeLa
In VIVO MODELNA, NA
CARGOFluorophore (FITC), Fluorophore (FITC)
PMID24697151, 24697151
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
2358 (PEPstrMOD), 2379 (PEPstrMOD),