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This page gives details of CPPsite entry with ID 2249
Primary information
CPPsite ID2249
PEPTIDE SEQUENCERKKRRQRRR
PEPTIDE NAMETat-PCP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONAcetylation
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONΦ, L-2-naphthylalanine,miniPEG, 8-amino-3,6-dioxaoctanoic acid
UPTAKE EFFICIENCYLower efficiency
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHEK293, HeLa, MCF-7, NIH 3T3, A549, Jurkat, H1650, and H1299 cells
CARGOPeptide [PCP, miniPEG-DE(pCAP)LI-NH2]
PMID24896852
PATENTUnknown
LENGTH9
Secondary StructureCCCCCSCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)