Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Browse Results ...

The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
VHL	DIVRSLYEI	KIDNEY	179	p.E186fs	c.557_557delA	Frame_Shift_Del	1	0.11	TUHR10TKB	N	7	0	0	N
VHL	DSLFLPISH	KIDNEY	143	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	6	0.11	A498	N	1	0	0	N
VHL	EIWKTTQMC	KIDNEY	186	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	1	0	0	N
VHL	EMPPGCPEP	KIDNEY	160	p.E160fs	c.480_481delGC	Frame_Shift_Del	4	0.11	VMRCRCW	N	0	0	0	N
VHL	FLPISHCQC	KIDNEY	146	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	7	0.11	A498	N	5	0	4	N
VHL	FVPSLNVDS	KIDNEY	136	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	1	0.11	A498	N	3	0	26	N
VHL	IVRSLYEIW	KIDNEY	180	p.E186fs	c.557_557delA	Frame_Shift_Del	2	0.11	TUHR10TKB	N	4	0	1	N
VHL	IWKTTQMCR	KIDNEY	187	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	2	0	0	N
VHL	KEMPPGCPE	KIDNEY	159	p.E160fs	c.480_481delGC	Frame_Shift_Del	5	0.11	VMRCRCW	N	2	0	0	N
VHL	KTTQMCRKT	KIDNEY	189	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	1	0	0	N
VHL	LFLPISHCQ	KIDNEY	145	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	6	0.11	A498	N	0	0	1	N
VHL	LKEMPPGCP	KIDNEY	158	p.E160fs	c.480_481delGC	Frame_Shift_Del	5	0.11	VMRCRCW	N	0	0	0	N
VHL	LNVDSLFLP	KIDNEY	140	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	5	0.11	A498	N	0	0	4	N
VHL	LPISHCQCI	KIDNEY	147	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	6	0.11	A498	N	14	0	4	N
VHL	LPVYTLKEM	KIDNEY	153	p.E160fs	c.480_481delGC	Frame_Shift_Del	1	0.11	VMRCRCW	N	13	0	0	N
VHL	LYEIWKTTQ	KIDNEY	184	p.E186fs	c.557_557delA	Frame_Shift_Del	6	0.11	TUHR10TKB	N	0	0	0	N
VHL	MPPGCPEPS	KIDNEY	161	p.E160fs	c.480_481delGC	Frame_Shift_Del	5	0.11	VMRCRCW	N	5	0	0	N
VHL	NVDSLFLPI	KIDNEY	141	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	5	0.11	A498	N	2	0	0	N
VHL	PGCPEPSQA	KIDNEY	163	p.E160fs	c.480_481delGC	Frame_Shift_Del	5	0.11	VMRCRCW	N	0	0	0	N
VHL	PISHCQCIL	KIDNEY	148	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	7	0.11	A498	N	0	0	0	N
VHL	PPGCPEPSQ	KIDNEY	162	p.E160fs	c.480_481delGC	Frame_Shift_Del	5	0.11	VMRCRCW	N	0	0	0	N
VHL	PSLNVDSLF	KIDNEY	138	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	3	0.11	A498	N	1	0	0	N
VHL	PVYTLKEMP	KIDNEY	154	p.E160fs	c.480_481delGC	Frame_Shift_Del	2	0.11	VMRCRCW	N	0	0	0	N
VHL	QMCRKTWSG	KIDNEY	192	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	0	0	0	N
VHL	RSLYEIWKT	KIDNEY	182	p.E186fs	c.557_557delA	Frame_Shift_Del	4	0.11	TUHR10TKB	N	1	0	0	N
VHL	SLFLPISHC	KIDNEY	144	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	6	0.11	A498	N	5	0	0	N
VHL	SLNVDSLFL	KIDNEY	139	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	4	0.11	A498	Y	11	11	0	N
VHL	SLYEIWKTT	KIDNEY	183	p.E186fs	c.557_557delA	Frame_Shift_Del	5	0.11	TUHR10TKB	N	4	0	0	N
VHL	TLKEMPPGC	KIDNEY	157	p.E160fs	c.480_481delGC	Frame_Shift_Del	5	0.11	VMRCRCW	N	2	0	0	N
VHL	TQMCRKTWS	KIDNEY	191	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	0	0	0	N
VHL	TTQMCRKTW	KIDNEY	190	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	1	0	0	N
VHL	VDSLFLPIS	KIDNEY	142	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	5	0.11	A498	N	1	0	0	N
VHL	VPSLNVDSL	KIDNEY	137	p.V142fs	c.426_429delTGAC	Frame_Shift_Del	2	0.11	A498	N	18	0	0	N
VHL	VRSLYEIWK	KIDNEY	181	p.E186fs	c.557_557delA	Frame_Shift_Del	3	0.11	TUHR10TKB	N	2	0	6	Y
VHL	VYTLKEMPP	KIDNEY	155	p.E160fs	c.480_481delGC	Frame_Shift_Del	3	0.11	VMRCRCW	N	0	0	0	N
VHL	WKTTQMCRK	KIDNEY	188	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	3	0	2	N
VHL	YEIWKTTQM	KIDNEY	185	p.E186fs	c.557_557delA	Frame_Shift_Del	7	0.11	TUHR10TKB	N	10	0	15	N
VHL	YTLKEMPPG	KIDNEY	156	p.E160fs	c.480_481delGC	Frame_Shift_Del	4	0.11	VMRCRCW	N	1	0	0	N
VHL	ANITPPVYT	KIDNEY	149	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	1	0	0	N
VHL	DLEWLTQER	LUNG	197	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	6	0	0	N
VHL	DNYRRLDIV	ENDOMETRIUM	173	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	7	0	0	N
VHL	ENYKRLDIV	ENDOMETRIUM	173	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	7	0	0	N
VHL	EWLTQERIA	LUNG	199	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	0	0	0	N
VHL	FANITPPVY	KIDNEY	148	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	8	0	4	N
VHL	GQLWLFRDA	KIDNEY	114	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	1	0	0	N
VHL	HSYRGQLWL	KIDNEY	110	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	Y	17	10	0	N
VHL	IFANITPPV	KIDNEY	147	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	3	0	0	N
VHL	IHSYRGQLW	KIDNEY	109	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	3	0	0	N
VHL	ITPPVYTLK	KIDNEY	151	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	Y	4	13	0	N
VHL	KDLEWLTQE	LUNG	196	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	0	0	0	N
VHL	KPDNYRRLD	ENDOMETRIUM	171	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	1	0	0	N
VHL	KPENYKRLD	ENDOMETRIUM	171	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	1	0	0	N
VHL	KRLDIVRSL	ENDOMETRIUM	176	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	Y	10	10	0	N
VHL	LEWLTQERI	LUNG	198	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	13	0	0	N
VHL	LVKPDNYRR	ENDOMETRIUM	169	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	6	0	1	N
VHL	LVKPENYKR	ENDOMETRIUM	169	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	6	0	1	N
VHL	NITPPVYTL	KIDNEY	150	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	Y	8	9	0	N
VHL	NVQKDLEWL	LUNG	193	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	8	0	0	N
VHL	NYKRLDIVR	ENDOMETRIUM	174	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	3	0	0	N
VHL	PDNYRRLDI	ENDOMETRIUM	172	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	2	0	0	N
VHL	PENYKRLDI	ENDOMETRIUM	172	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	1	0	0	N
VHL	PIFANITPP	KIDNEY	146	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	0	0	0	N
VHL	PNVQKDLEW	LUNG	192	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	0	0	0	N
VHL	PPVYTLKER	KIDNEY	153	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	0	0	0	N
VHL	QKDLEWLTQ	LUNG	195	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	0	0	0	N
VHL	QLWLFRDAG	KIDNEY	115	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	2	0	0	N
VHL	QPIFANITP	KIDNEY	145	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	0	0	0	N
VHL	RGQLWLFRD	KIDNEY	113	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	0	0	0	N
VHL	RIHSYRGQL	KIDNEY	108	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	9	0	0	N
VHL	RRIHSYRGQ	KIDNEY	107	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	1	0	0	N
VHL	RSLVKPDNY	ENDOMETRIUM	167	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	7	0	0	N
VHL	SLVKPDNYR	ENDOMETRIUM	168	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	5	0	0	N
VHL	SLVKPENYK	ENDOMETRIUM	168	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	Y	6	12	0	N
VHL	SYRGQLWLF	KIDNEY	111	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	Y	3	9	0	N
VHL	TPPVYTLKE	KIDNEY	152	p.L153P	c.458T>C	Missense_Mutation	1	0.11	TUHR14TKB	N	0	0	0	N
VHL	VKPDNYRRL	ENDOMETRIUM	170	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	Y	10	12	0	N
VHL	VKPENYKRL	ENDOMETRIUM	170	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	10	0	0	N
VHL	VQKDLEWLT	LUNG	194	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	2	0	0	N
VHL	VRSLVKPDN	ENDOMETRIUM	166	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	2	0	23	N
VHL	VVRSLVKPD	ENDOMETRIUM	165	p.E173D	c.519G>T	Missense_Mutation	1	0.11	JHUEM7	N	0	0	17	N
VHL	WLTQERIAH	LUNG	200	p.R200W	c.598C>T	Missense_Mutation	1	0.11	HCC4006	N	2	0	7	N
VHL	YKRLDIVRS	ENDOMETRIUM	175	p.R176K	c.527G>A	Missense_Mutation	1	0.11	TEN	N	3	0	38	N
VHL	YRGQLWLFR	KIDNEY	112	p.H115Q	c.345C>A	Missense_Mutation	1	0.11	SNU1272	N	5	0	10	N
VHL	DNVRSLYED	KIDNEY	179	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	0	0	0	N
VHL	DNVRSLYED	KIDNEY	179	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	0	0	0	N
VHL	ENYRRLDNV	KIDNEY	173	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	6	0	0	N
VHL	ENYRRLDNV	KIDNEY	173	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	6	0	0	N
VHL	LDNVRSLYE	KIDNEY	178	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	0	0	0	N
VHL	LDNVRSLYE	KIDNEY	178	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	0	0	0	N
VHL	NVRSLYEDL	KIDNEY	180	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	6	0	0	N
VHL	NVRSLYEDL	KIDNEY	180	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	6	0	0	N
VHL	NYRRLDNVR	KIDNEY	174	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	2	0	0	N
VHL	NYRRLDNVR	KIDNEY	174	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	2	0	0	N
VHL	PENYRRLDN	KIDNEY	172	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	0	0	0	N
VHL	PENYRRLDN	KIDNEY	172	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	0	0	0	N
VHL	RLDNVRSLY	KIDNEY	177	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	8	0	0	Y
VHL	RLDNVRSLY	KIDNEY	177	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	8	0	0	Y
VHL	RRLDNVRSL	KIDNEY	176	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	Y	10	10	0	N
VHL	RRLDNVRSL	KIDNEY	176	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	Y	10	10	0	N
VHL	YRRLDNVRS	KIDNEY	175	p.I180N	c.539T>A	Missense_Mutation	1	0.22	769P	N	4	0	45	N
VHL	YRRLDNVRS	KIDNEY	175	p.I180N	c.539T>A	Missense_Mutation	1	0.22	A704	N	4	0	45	N